EXAMINE THIS REPORT ON CAFERGOT DISCONTINUED

Check Carefully (one)mitotane decreases amounts of ergotamine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Mitotane is a strong inducer of cytochrome P-4503A4; keep track of when coadministered with CYP3A4 substrates for achievable dosage changes.Therefore, in accordance with E.O. 13132, it is determined that this ac